Cannabis Use Linked With Increased Risk for Diabetic Ketoacidosis in T1D Adults

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By : dLife Editors

Adults with Type 1 diabetes may be twice as likely to develop diabetic ketoacidosis (DKA) when they use cannabis regularly than when they avoid the drug, according to a new study.

The researchers looked at the frequency of diabetic ketoacidosis (DKA) in cannabis users compared with those who did not use the drug from the T1D Exchange clinic registry (T1DX).

How was the Study Conducted?

Researchers looked at the association between cannabis use by looking at the total substance score for cannabis (TSC) and DKA in the past 12 months.

They found that of 932 adults with Type 1 diabetes, 61 had a TSC >4, which classified them as moderate cannabis users.

Adjusting for sex, age at study visit, and HbA1c, cannabis use was associated with a two-fold increase in risk for DKA among adults with Type 1 diabetes.

The authors conclude that the use of cannabis is associated with an increased risk for DKA among adults in the T1D Exchange clinic registry. They state that healthcare providers should inform their patients of the potential risk of DKA with cannabis use.

The study was conducted by researchers at the Colorado School of Public Health, University of Colorado Anschutz Medical Campus in Aurora and Jaeb Center for Health Research, in Tampa, FL.

The has been published in Diabetes Care.


  1. Diabetes Care. (2019, October 18). Cannabis Use Is Associated With Increased Risk for Diabetic Ketoacidosis in Adults With Type 1 Diabetes: Findings From the T1D Exchange Clinic Registry. Retrieved November 26, 2019, from